THE EFFECTS OF THE INTENSITY OF CIGARETTE USE AND ANTIRETROVIRAL THERAPY ON THE BLOOD LIPID PROFILE OF AN IRISH HIV PERSON
Keywords:Lipid, cholesterol, high density lipoprotein, low density lipoprotein, triglyceride, HIV, AIDS, human immunodeficiency virus, antiretroviral, anti-retroviral, antiretroviral drug, smoking, cigarette, tobacco
Context: There are numerous studies on the effects of smoking and antiretroviral use separately on a HIV patient’s blood lipid profile, however there has never been a study conducted that measures the intensity of cigarette use combined with antiretroviral therapy on a patient’s blood lipid profile. Aims: To assess the effects of the intensity of cigarette usage and antiretroviral therapy on a patient’s blood lipid profile. Setting and Design: This cross-sectional study was carried out in a regional HIV clinic in Cork University Hospital between June 2016 and August 2016. Methods: 40 patients were interviewed in order to gather cigarette usage data and patient files were reviewed in order to gather blood lipid profile results and antiretroviral therapy data. Results: There was no statistically significant difference (P>0.05) in the means of cholesterol (4.99 vs 5.47), high-density lipoprotein (1.22 vs 1.07), low-density lipoprotein (3.13 vs 3.03), nor triglycerides (1.54 vs 2.45) in smokers versus non-smokers. Low-density lipoprotein in mild and moderate smokers was increased compared to non-smokers. Conclusions: These results show that smoking combined with nucleoside reverse transcriptase inhibitor use has no significant change in blood lipid measurements when compared to controls.
How to Cite
Authors retain ownership of the copyright for their manuscript.